When addressing the serious concern of colon cancer, many people wonder about the effectiveness of standard imaging tools like the CT (Computed Tomography) scan. The direct answer is yes, a CT scan can certainly detect cancer in this area by creating detailed cross-sectional images of the abdomen and pelvis. This advanced technology excels at revealing abnormal tissue growth, clearly showing the size and precise location of tumors within the colon wall. Furthermore, the CT scan is invaluable for staging the disease, checking if and where the cancer has spread (or metastasized) to other organs like the liver or lungs.
However, there is a crucial distinction to be made regarding its role. While effective for detection and staging, a traditional CT scan is generally not used as the first-line screening method for the average, asymptomatic patient. This is because these scans are less adept at detecting tiny precancerous growths called polyps or subtle changes in the colon’s inner lining (mucosa) compared to procedures like colonoscopies. A CT scan is often reserved for patients who cannot undergo a colonoscopy or for follow-up and monitoring once cancer has already been diagnosed. Here’s everything you need to know.
What is a CT scan?
A CT scan is a medical imaging procedure that utilizes X-rays and computer technology to create a detailed cross-sectional image of the body’s interior. Trauma is the usual CT indication. This includes someone who has been in an accident or fallen, to rule out a fracture, as explained by Hopkins Medicine.
This procedure enables medical professionals to gain a firsthand look at internal body structures, including bones, organs, blood vessels and soft tissues. A CT scan provides detailed images compared to regular X-rays.
How it works
Unlike a regular X-ray, which uses a fixed X-ray tube, a CT scan uses a large, circular machine where the CT scanner rotates around your body, sending X-ray beams from different angles, per the National Institute of Biomedical Imaging and Bioengineering.
As Tunde Rasheed, B.Sc. Researcher explains, “The CT scan uses unique digital X-ray detectors. The X-ray detector is located opposite the X-ray source. After a full body scan, X-rays are picked up by the detectors and transmitted to a specialized computer.” The computer collects the data and regenerates it into either 2D or 3D images, depending on the technology used. The main advantage of this procedure is that it enables the rotation of 3D images in space, making it easier for healthcare professionals to pinpoint the exact location of a problem.
What a CT scan can detect
A CT scan can be used to detect a variety of medical conditions or abnormalities, including tumors, injuries such as fractures and conditions affecting the brain, heart, lungs and abdomen.
According to the Cleveland Clinic, some examples include:
- Broken bones
- Heart disease
- Types of cancer
- Brain injuries
- Kidney stones
- Blood clots
Limitations
While a CT scan is a beneficial procedure in the medical field, it also presents its challenges, which, if safety measures are not taken into account, can lead to undesired results. Radiation exposure is a primary concern when undergoing a CT scan procedure. While it helps to detect cancers and other abnormalities, the CT scan technique uses ionizing radiation, which studies note can increase the risk of cancer over time, especially if the procedure is used more than once.
Risks and safety considerations
The safety of a patient is usually a top priority among healthcare professionals. This aligns with established medical guidelines and standards, ensuring that patient safety is of paramount importance. While a CT scan is usually considered safe, it poses a significant health risk, especially in cases of repeated scans. This procedure uses ionizing radiation and continued exposure to radiation can damage DNA (deoxyribonucleic acid) and increase the risk of developing cancer, as shared by the National Institute of Health.
Additionally, the European Journal of Radiology shares that some CT scans use a special dye called contrast material to enhance the clarity of the image. While the application of this material is rare, it can cause allergic reactions when applied. Safety considerations are essential before undergoing a CT scan. As a patient undergoing the test, it’s beneficial to inform your healthcare expert about allergies and kidney problems. Also, to ensure the safety and integrity of the procedure, remove all metallic objects.
Expectant women should inform their healthcare professionals about their pregnancies as exposure to radiation can affect the fetus, leading to birth defects, studies point out. For children, the procedure should use lower radiation doses tailored to size and age. Healthcare professionals should only use a CT scan when vital and when other tests, such as an ultrasound or an MRI, are insufficient.
Alternatives or additional tests
Where a CT scan is not necessary, your healthcare expert can recommend alternative, suitable and safe procedures, which include mostly non-radiation alternatives such as MRI and ultrasound. Magnetic Resonance Imaging (MRI) utilizes a strong magnetic field and radio waves to create detailed images of soft tissues and bones. This procedure is most suitable for imaging soft tissues, such as the brain, and detecting certain cancers, according to the Cleveland Clinic.
Additionally, the Cleveland Clinic notes that another suitable alternative is ultrasound. Unlike a CT scan, this test technique uses high-frequency sound waves to generate images of internal body organs, tissues and structures. Considered safe for expectant women, ultrasound is used primarily to monitor fetal development during pregnancy and guide medical procedures like biopsies. A biopsy is a medical procedure used to remove a sample of body tissue or cells for laboratory testing to diagnose a disease.
What are the warning signs of colon cancer?
Colon cancer is a type of cancer that occurs in the colon. It’s also called colorectal cancer when it includes the rectum, per the Mayo Clinic. This type of cancer begins when abnormal cells in the lining of the colon grow uncontrollably, leading to the formation of polyps. The Mayo Clinic also notes that a polyp is an abnormal tissue growth on a mucous membrane, not only in the colon but also in other parts such as the nose and uterus.
Colon cancer develops when normal, abnormally formed polyps. Over time, these polyps may turn into invasive cancer. If left untreated, it can spread to other organs, particularly the liver, lungs or lymph nodes. There are several warning signs that you might be a victim of colon cancer, Acta Oncologica explains. The first notable sign is a change in bowel habits. This will be evident through a change in stool consistency and a feeling that your bowel does not empty properly.
Other signs include:
- Blood in stool
- Unexplained weight loss
- Fatigue or weakness
- Persistent abdominal pain
If you notice these symptoms, consult a medical expert for examination and professional guidance.
How often is colon cancer missed on a CT scan?
While the abdominal CT scan is a powerful diagnostic tool, clinicians must recognize its limitations in consistently detecting colon cancer. Research highlights a significant diagnostic gap: according to Science Direct, colon cancer is missed in approximately 20% of routine abdominal CT tests performed on patients who are subsequently proven to have the disease.
This statistic is critical because these are non-dedicated CTs (scans ordered for general abdominal symptoms), not specialized virtual colonoscopies. This omission underscores the necessity for healthcare providers to remain highly vigilant and aware of the restricted sensitivity of standard CT imaging, emphasizing the need for supplementary testing, such as colonoscopy, when clinical suspicion for colon cancer remains high.
What can be mistaken for colon cancer on a CT scan?
Sometimes, a CT scan may not accurately detect colon cancer, as other conditions can look similar. This can lead to a possible misdiagnosis or the need for further testing. Both colonoscopy and biopsy are better alternatives to confirm the diagnosis.
Conditions that can be mistaken for colon cancer on a CT scan are:
- Diverticulitis: This is a condition that causes inflammation or infection of small pouches on the colon wall. It can appear as wall thickening, fat stranding and a mass-like area according to the Mayo Clinic.
- Inflammatory colitis: This condition is triggered by infections, Crohn’s disease or ulcerative colitis, the Mayo Clinic explains. It can cause bowel walls to thicken.
Bottom line
A CT scan can indeed detect colon cancer by showing tumors, their size, location and possible areas of spread. However, this procedure is not ideal for early detection as it can miss small polyps or early-stage cancers.
A CT scan carries risks, including radiation exposure and possible allergic reactions to contrast dye. Certain conditions, such as diverticulitis or colitis, can appear similar in a CT scan, potentially leading to a false diagnosis. Therefore, for accurate diagnosis and screening, colonoscopy remains the appropriate procedure, as it allows for direct visualization and biopsy of suspicious tissue.
Frequently Asked Questions
Where is colon cancer pain?
Generally, colon pain is in the abdomen, often as cramping, bloating or discomfort. However, the exact location can vary, ranging from right-sided pain, left-sided pain or rectal pressure or pain.
Why do I need a colonoscopy after a CT scan?
Since a CT scan cannot confirm if abnormalities like wall thickening are cancerous, the preferred method is a colonoscopy. It enables healthcare professionals to directly visualize the inside of the colon, remove polyps and take biopsies for laboratory testing.
Citations
Fayad LM. CT Scan Versus MRI Versus X-Ray: What Type of Imaging Do I Need? Johns Hopkins Medicine. Published 2024. https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/ct-vs-mri-vs-xray
NIH. Computed Tomography (CT). National Institute of Biomedical Imaging and Bioengineering. Published 2022. https://www.nibib.nih.gov/science-education/science-topics/computed-tomography-ct
Cleveland Clinic. CT Scan (Computed Tomography): What is It, Preparation & Test Details. Cleveland Clinic. Published June 13, 2023. https://my.clevelandclinic.org/health/diagnostics/4808-ct-computed-tomography-scan
Patel PR, De Jesus O. CT Scan. PubMed. Published January 2, 2023. https://www.ncbi.nlm.nih.gov/books/NBK567796/
National Institutes of Health. Radiation from CT scans and cancer risks. National Institutes of Health (NIH). Published April 28, 2025. https://www.nih.gov/news-events/nih-research-matters/radiation-ct-scans-cancer-risks
van der Molen AJ, van de Ven AAJM, Vega F, Dekkers IA, Laguna JJ. Rare delayed hypersensitivity reactions to contrast media: Severe cutaneous adverse reactions. European Journal of Radiology. 2024;183:111908. doi:https://doi.org/10.1016/j.ejrad.2024.111908
Yoon I, Slesinger TL. Radiation Exposure in Pregnancy. PubMed. Published May 1, 2023. https://www.ncbi.nlm.nih.gov/books/NBK551690/
Cleveland Clinic. MRI (Magnetic Resonance Imaging). Cleveland Clinic. Published May 9, 2022. https://my.clevelandclinic.org/health/diagnostics/4876-magnetic-resonance-imaging-mri
Cleveland Clinic. Ultrasound: What It Is, Purpose, Procedure & Results. Cleveland Clinic. Published April 12, 2022. https://my.clevelandclinic.org/health/diagnostics/4995-ultrasound
Mayo Clinic. Colon Cancer – Symptoms and Causes. Mayo Clinic. Published July 27, 2023. https://www.mayoclinic.org/diseases-conditions/colon-cancer/symptoms-causes/syc-20353669
Mayo Clinic. Colon polyps – Symptoms and causes. Mayo Clinic. Published March 2, 2023. https://www.mayoclinic.org/diseases-conditions/colon-polyps/symptoms-causes/syc-20352875
Borre M, Fassov J, Juul T, et al. Diet and bowel symptoms among colon cancer survivors. Acta Oncologica. 2022;61(10):1192-1199. doi:https://doi.org/10.1080/0284186x.2022.2101901
Mayo Clinic. Diverticulitis – Symptoms and causes. Mayo Clinic. Published October 22, 2022. https://www.mayoclinic.org/diseases-conditions/diverticulitis/symptoms-causes/syc-20371758
Mayo Clinic. Inflammatory bowel disease (IBD) – Symptoms and causes. Mayo Clinic. Published December 18, 2024. https://www.mayoclinic.org/diseases-conditions/inflammatory-bowel-disease/symptoms-causes/syc-20353315
